XoNovo

Small-molecule Drugs for Neurodegenerative Diseases

Company Name
Updating Date
Neurotech Category
Market Category
Target Market
Technologies
Company Founded Year
Company Number of Employees
XoNovo
Biotechnology & Biopharmaceutical
01/01/2013
"11-50"
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XoNovo is a preclinical-stage biopharmaceutical company engaged in the development of small-molecule therapeutics for preventing the progressive loss of neuronal function across multiple neurodegenerative diseases.

The company's short-term focus is on its lead drug, XN001, in support of filing an investigational new drug application for Batten disease (BD), also known as neuronal ceroid lipofuscinoses, a fatal neurodegenerative orphan disorder.

XoNovo utilizes a novel approach of selective modulation of autophagy and axonal transport machinery in neurons. XN001 has been extensively tested in both in-vitro and in-vivo models, showing promising results in neurodegenerative diseases including BD, Alzheimer's disease, glioblastoma, muscular dystrophy, and tuberous sclerosis.